José Greenspon, MD, FACS, FAAP

Yosef Jose Greenspon, M.D.José Greenspon, MD, FACS, FAAP
Assistant Professor of Surgery 
Division of Pediatric Surgery
Department of Surgery
Saint Louis University School of Medicine
SSM Cardinal Glennon Children’s Medical Center

Postgraduate Clinical training:

Pediatric Surgery Resident

St. Louis Children’s Hospital/Washington University SOM

St. Louis, MO


Chief Resident of Surgical Education

University of Maryland Medical System

Baltimore, MD


Resident in Surgery

University of Maryland Medical System

Baltimore, MD

Categorical Intern in Surgery

University of Maryland Medical System

Baltimore, MD



Postgraduate Research:

Postdoctoral Research Fellow (T32 Award)                                      06/05-06/07

Role of sphingolipids (S1P) and polyamines in

intestinal epithelial cell integrity and apoptosis

Cell Physiology Laboratory

Department of Surgery

University of Maryland School of Medicine and

Baltimore VA Medical Center

Baltimore, MD

Principal Investigator: Douglas J. Turner, MD


Postdoctoral Research Fellow 06/06-06/08

Genetic polymorphisms related to inflammatory response

and survival in cholestatic injury in mice.

Mucosal Biology Research Center

University of Maryland School of Medicine

Baltimore, MD

Principal Investigator: Terez Shea-Donohue, Ph.D.


George Washington University School of Medicine

Washington, D.C.

Doctor of Medicine

University of Maryland, College Park

College Park, MD

B.S. in Microbiology

Board Certification

American Board of Surgery, General Surgery

American Board of Surgery, Pediatric Surgery


Professional Society memberships

American Pediatric Surgical Association, Candidate Member                      
American College of Surgeons, Associate Member
American Academy of Pediatrics, Fellow Member                                      
Association for Academic Surgery

Honorary Societies, Honors and Awards

1. Ambassador Choice Award Nominee for Exceptional Medical Care                  2015

SSM Cardinal Glennon Children’s Medical Center

2. Ambassador Choice Award Recipient for Exceptional Medical Care                 2014

SSM Cardinal Glennon Children’s Medical Center

3. Sponseller Surgical Research Award, Second Place                                            2008

University of Maryland School of Medicine

4. Sponseller Surgical Research Award                                                                    2007

University of Maryland School of Medicine

5. NIH Research Training Fellowship in Gastroenterology                                      2006-2007

Principal Investigator: Jean-Pierre Raufman, M.D.

(two-year fellowship award)

6. Department of Surgery Education Award                                                                       2006

7. Arnold P. Gold Humanism and Honor Society Resident Award                                    2006

8. Humanism and Excellence in Teaching Resident Award                                     2005

9. University of Maryland School of Medicine

10. Alpha Omega Alpha Medical Honor Society                                                        2005

11. Sigma Alpha Omicron Microbiology Honor Award                                            1999

University of Maryland, College Park

12. Who's Who Among American College Students                                                 1998

13. OMSE Academic Excellence Honors                                                                    1997-1999

University of Maryland, College Park

14. Dean’s List (five semesters), University of Maryland, College Park                   1995-1999

15. Highly Commended Medical Book Award for Pediatric Gastroenterology: 2015

A Color Handbook. British Medical Association


Professional Services

Clinical Competency Committee, Pediatric Surgery Fellowship                    2013present

Program Evaluation Committee, Pediatric Surgery Fellowship                     2013-present

Surgical Peer Review Committee                                                                   2012-current SSM Cardinal Glennon Children’s Medical Center

Pediatric Trauma Peer Review Committee                                                     2010-2012

St. Louis Children’s Hospital/Washington University SOM

Clinical Information Systems, Committee on Perioperative Care,                 2007-2010                   UMSOM

General Surgery Curriculum Committee, UMSOM                                       2005-2010

Webmaster University of Maryland General Surgery Resident Site,             2005-2008                   UMSOM

Current and Past Teaching Responsibilities

Faculty Preceptor for MS2 Introduction to Clinical Medicine. St Louis       2014-present

University SOM

Medical Student General Surgery Clerkship Lecturer, UMSOM                  2004-2010

Anatomy Instruction. University of Maryland School of Medicine              2003-2008                   (UMSOM).  Participated in medical student instruction of abdominal and

thoracic gross anatomy

Thalamus Club, George Washington University School of Medicine            1999-2001

Instructed underclassmen in dissection anatomy/neuroanatomy


SSM Cardinal Glennon Children’s Medical Center                                       2012-present

Responsible for multiple clinical projects. No external funding.

University of Maryland School of Medicine, Dept of Surgery,                     2006-2008

Division of Pediatric Surgery. Samuel Alaish, M.D., Terez

Shea-Donohue, Ph.D. Studied the role of genetic polymorphisms

in response to cholestatic injury in mice.

University of Maryland School of Medicine & Baltimore VA                      2005-2007

Medical Center, Baltimore, MD

Jin-Yiang Wang, M.D., Ph.D., Douglas J. Turner, M.D., Terez

Shea-Donohue, Ph.D.

George Washington University Medical Center                                             2002-2003

Bruce A. Orkin, M.D. Studied the role of surgical versus

expectant management in recurrence of thrombosed external


George Washington University Medical Center                                             2002

Bruce A. Orkin, M.D.  Worked on characterization of anal

carcinoma - in situ progression in HIV-positive versus noninfected


National Institute of Child Health and Human Development, NIH              1999

Doug J. Fields, M.D. Ph.D.  Explored the effects of impulse activity

on gene expression, myelination, and synaptic function of neurons.

National Institute of Neurological Disorders and Stroke, NIH                     07/98-04/99

John Hallenbeck, M.D.  Studied the role of NF-κB with intranuclear

p300, to chemical (TNF-α exposure) and hypoxic tolerance in

astrocytes and neurons.

University of Maryland, College Park                                                            Summer 1998

Stephen Hutcheson, Ph.D.  Developed protocols for the use of

mutant strains of Xanthomonas in surveillance of plant pathogens

in the environment.


1.         Ginis I, Jaiswal R, Klimanis D, Liu J, Greenspon J, Hallenbeck JM.  TNF-alpha-induced tolerance to ischemic injury involves differential control of NF-kappaB transactivation: the role of NF-kappaB association with p300 adaptor. J Cereb Blood Flow Metab. 2002 Feb;22(2):142-152.

2.         Greenspon J, Williams SB, Young HA, Orkin BA.  Thrombosed external hemorrhoids: outcome after conservative or surgical management. Dis Colon Rectum. 2004 Sep;47(9):1493-1498.

3.         Williams SB, Greenspon J, Young HA, Orkin BA.  Small bowel obstruction: conservative vs. surgical management. Dis Colon Rectum. 2005 Jun;48(6):1140-1146.

4.         Liu L, Guo X, Rao, JN, Zou, TT, Marasa BS, Greenspon J, Casero RA, Wang J-Y.  Polyamine-Modulated c-Myc Regulates p21 Transcription through proximal region of its promoter in normal intestinal epithelium. Biochem J. 2006 Sep 1;398(2):257-67.

5.         Turner DJ, Martin PC, Rao JN, Greenspon J, Zou T, Bass BL, Wang JY, Strauch ED. Substance P regulates migration in rat intestinal epithelial cells. Ann Surg. 2007 Mar; 245(3):408-414.

6. Greenspon J, Li R, Rao JN, Strauch ED, Wang JY, Turner DJ.  Sphingosine-1-Phosphate upregulates E-cadherin and enhances intestinal mucosal permeability.  J Surg Res.  2007;137(2):256.

7. Greenspon J, Li R, Rao JN, Marasa BS, Zhang AH, Strauch ED, Wang JY,

Turner DJ.  Sphingosine-1-Phosphate protects intestinal epithelial from apoptosis through Akt activation.  Dig Dis Sci 2009 Mar;54(3):499-510.  Epub 2008 Jul 25.

8.         Alaish SM, Greenspon J, Strauch ED, Sun CC. Intraabdominal pulmonary sequestration presenting with elevated urinary normetanephrine levels. J Pediatr Surg. 2009 Mar;44(3):e11-4.

9. Greenspon J, Perrone E, Alaish SM. Shoshin Beriberi mimicking central line sepsis in a child with short bowel syndrome. World J Pediatr. 2010 Nov;6(4):366-368.

10.       Greenspon J, Yu J, Warner BW. Late volvulus of an intrathoracic gastric pull-up. J Pediatr Surg 2012 Apr;47(4):792-4.

11.       Alaish SM, Smith AD, Timmons J, Greenspon J et. al. Gut microbiota, tight junction protein expression, intestinal resistance, bacterial translocation and mortality following cholestasis depend on the genetic background of the host. Gut Microbes. 2013 Jul 1;4(4):292-305.

12.       Bani Hani M, Kamangar F, Goldberg S, Greenspon J, et. al. Pneumatosis and portal venous gas: do CT findings reassure? J Surg Res. 2013 Jun 29

13.       Winchester LM, Puckett Y, Greenspon J, Vogler CA Mediastinal granular cell tumor in a 16-year-old boy: A surgical and pathologic perspective. Pediatr Dev Pathol. 2015 Jul 17.

14. Puckett Y, Agarwal A, Batanian JR, Greenspon J. Case Report of a 3-year-old Girl with Pleuropulmonary Blastoma and Family History of a Tumor Predisposition Syndrome with c. 2830 Gene Mutation in DICER1. Journal of Pediatric Surgery Case Reports 06/2015; 25(8).
15. Puckett Y, Caley M, Farmakis SW, Bonacorsi LW, Fitzpatrick CM, Chatoorgoon K, Greenspon J, Vane DW. Imaging Prior to Transfer to Designated Pediatric Trauma Centers (PTCs) Exposes Children to Excess Radiation. J Trauma Acute Care. 2016 Apr 5
16. Huddleston CB, Greenspon J, Would you buy this car  without a warranty J
Thorac Cardiovasc Surg. 2016 June2 S0022-5223(16)30490-1
17. Puckett Y, Greenspon J, Fitzpatrick C, Vane D, Bansal S, Rice M,
Chatoorgoon  K.    Utility of hospital admission for pediatric intussusceptions.     Pediatr Surg Int 2016    Aug:32(8):805-9

Book chapters, monographs, case reports, electronic media,

non-peer reviewed articles

1. Greenspon J, Fialkowski E, Warner BW. “Necrotizing Enterocolitis” in Pediatric Gastroenterology:  A Color Handbook.

2. Huddleston C, Greenspon J. “The Chest Cage-Chest Wall Deformities” in Shield’s General Thoracic Surgery 8th Edition

3. Greenspon J, Lipskar A, Villalona G, Chatoorgoon K, “Crohn Disease” in the Pediatric Surgery NaT, May 1, 2016 (